In-office patch myringoplasty

A tympanic membrane perforation is more than simply a hole in the eardrum — it causes or augments hearing loss, significantly reducing patient's quality of life. The impact problems resulting from communication disorders should not be underestimated. In this paper, we introduce office-based growth factor enabled repair. Advances tissue engineering have delivered major breakthrough treatments available: development therapy involving body's self-repair system. has natural capacity to regenerate. Elucidating and understanding mechanism regeneration inspired safer convenient therapy, which may well tolerated by patients. This treatment involves enlarging perforations providing gelatin sponge impregnated with basic fibroblast as substrate.